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    Named a way to prevent Alzheimer's disease

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    Brazilian scientists from the University of Sao Paulo have named a way to prevent Alzheimer’s disease or delay the onset of symptoms through strength training. The results of the study were published in the journal Frontiers in Neuroscience.

    In the experiment, the authors examined genetically modified mice with a mutation that accumulated beta-amyloid plaques associated with Alzheimer’s disease in their brains. The test subjects were specially trained to climb a ladder 110 centimeters high with an inclination of 80 degrees and a distance between the rungs of two centimeters. Attached to their tails were weights corresponding to 75, 90, and 100 percent of their body weight. The test simulated certain types of strength training for people in fitness centers. The goal of the specialists was to monitor the neuroprotective processes of animals. Related materials: Nothing to breathe. How oxygen affects the aggressiveness of cancerous tumors After four weeks of exercise, blood samples were taken from the subjects to measure plasma levels of corticosterone, a hormone that corresponds to cortisol in humans. An increase in the level of this hormone occurs in response to stress, and it also increases the risk of developing Alzheimer’s disease. The researchers found that corticosterone levels were normal (identical to animals with no signs of dementia) in mice that exercised. Subsequent analysis of their brain tissue showed a decrease in beta-amyloid plaque formation.The findings of the work confirm that physical activity can reverse the neuropathological changes that cause the clinical symptoms of Alzheimer’s disease.

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